1, 2, 3, 9-tetrahydroquinazoline-3, 7-diol was originally isolated from the Tecomaria capensis. It is also known as capehoney suckle belonging to the family Bignonaceae. It (1, 2, 3, 9-tetrahydroquinazoline-3, 7-diol) is a major constituent of the species Tecomaria capensis (Thunb.) Spach. On silica gel GF254 TLC plates the chromatoplate analytical thin layer chromatography was accomplished. It was developed with toluene: ethyl acetate (7:3 v/v) as mobile phase. In this study, isolation of 1, 2, 3, 9-tetrahydroquinazoline-3, 7-diol was achieved by preparative TLC. The compound thus isolated was characterised by Mass, H1 NMR and FT-IR spectral analysis. Mass spectral data shows molecular ion peak of m/z=204.22. Antimicrobial activity was measured against Klebsiella pneumoniae, Staphylococcus subtillis, Escherichia coli and Staphylococcus aureus and anti-inflammatory activity was done in-vitro by using HRBC membrane stabilization method.
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